Dhammaan wakiilada liiska daroogooyinka-makrolid - daawooyinka lidka ku ah bakteeriyada. Dhismaha kiimikadoodu waxay ku saleysan tahay giraanta lactone macrocyclic. Sidaa awgeed - magaca kooxda. Waxaa loo isticmaalaa in lagu xakameeyo noocyada kala duwan ee bakteeriya. Dhibaatada ka dhalatay dhaqaalahani waa mid waxtar leh, daawada ayaa si aad ah u isticmaala.
Xaaladaha noocee ayaa ah daawooyinka kooxda macrolideed?
Faa'iidada ugu weyn ee macrolide waa in ay ka firfircoon yihiin waxyeellada Gram-positive ee cocci. Antibiyootikada kooxdani waxay si fudud ula qabsan kartaa pneumococci, streptococci pyogenic, mycobacteria. Waxyaabaha kale, waxay burburiyaan:
- legionella;
- spirochaetes;
- Chlamydia;
- xarumaha (wax kasta oo ka baxsan marka laga reebo B. fragilis);
- Listeria;
- mycoplasma;
- Hingaplasmas;
- Campylobacter iyo qaar ka mid ah sheyga kale ee waxyeelada leh.
Iyadoo ku saleysan liiskan, calaamadaha ugu muhiimsan ee loogu talagalay isticmaalka daawooyinka makrolida ayaa la sameeyey. U dir daawooyinka:
- streptococcal tonsilofaringitis;
- sinusitis-ba'an ;
- xiiq-dheerta;
- ka sii daridda bronchitis joogta ah;
- Nafaqada bulshada ee loo yaqaan 'pneumonia' (oo ay ku jirto qoyaan);
- gawracatada;
- faafista cudurka;
- waraabowga;
- Chlamydia;
- mycobacteriosis;
- toxoplasmosis;
- extramural lymphogranulomas;
- finan daran;
- periodontitis.
Xaaladaha qaarkood, macrolideedka waxaa loo isticmaalaa maaha oo keliya daaweynta, laakiin sidoo kale ka hortagga. Sidaa awgeed, tusaale ahaan, daawada ka hortagga bakteeriyada waxay kaa caawineysaa in aad ka hortagto xiiqdheerta dadka qaba xiriirka dadka qaba cudurka. Antibiyootikada kooxdan ayaa sidoo kale loo qoondeeyay sanbabada bukaanada kuwaas oo ah kuwa sidayaasha ah meningococcus. Waxay noqon karaan ka hortag wanaagsan oo loo yaqaan 'rotatism' ama 'endocarditis'.
Magacyada daroogada-antibiyootikada ee macrolide
Iyada oo ku xidhan inta mitir ee kaarbooni ku jirto wareegga lakin, daawooyinka waxay u qaybsan yihiin kooxo 14-, 15 ama 16-xubnood. Marka lagu daro xaqiiqda ah in daawooyinka bakteeriyadani ay burburiyaan bini'aadamka, waxay sidoo kale gacan ka geystaan xoojinta difaaca waxayna ka takhalusi kartaa inaysan si firfircoon ugu socon geedi socodka bararka.
Daawooyinka antibiyootigga ee ugu weyn-macroolayda waxaa ka mid ah daroogooyinka sida:
- Erythromycin waa in la qaataa cuntada ka hor. Haddii kale, bioavailability ayaa si weyn loo yareeyn doonaa. In kasta oo xaqiiqda ah in ay tahay daawo adag oo lid ku ah, iyada oo baahida degdegga ah ee cabitaanka loo ogolyahay xitaa inta lagu jiro uurka iyo nuujinta.
- Spiramycin way firfircoon tahay xittaa ka soo horjeeda bakteeriyada kuwaas oo la qabsata 14-iyo 15-xubnood ee macrolideed. Fiirinta istiraatiijiga ah ee unugyada ayaa aad u sarreeya.
- Daawada macrolide ee loo yaqaan " Clarithromycin" , waxay la dagaallantaa Helicobacter iyo mycobacteria.
- Daaweynta Roxithromycin ayaa si fiican u dulqaadan kara bukaanada.
- Azithromycin waa mid aad u xoog badan oo ah in la qaato hal mar maalintii.
- Caan ka ah Josamycin waxaa lagu sharaxay waxqabadyada ka dhanka ah badi noocyo adkaysi u ah strepto- iyo staphylococci.
Dhamaanba dhammaan makrolidyada liiska daroogooyinka ayaa loo qori karaa boronkiitada. Marka lagu daro kuwaan, si loola dagaallamo bakteeriyada waxaa loo isticmaali karaa:
- Dynabac;
- Ilozon;
- Azidrop;
- Azivok;
- Zimbactur;
- Wilprafen;
- Binocular;
- Benzamycin;
- Azicid;
- Klabaks;
- Azitral;
- Esparoxy;
- Brilid;
- Rovamycin;
- Crixan;
- Macropean;
- Xeeladda;
- Rulicin;
- Isugeynaya ;
- Hemomycin;
- Zitnob;
- Kispar;
- Sumatrolide Solute;
- Culimada
- Elrox;
- Coater;
- Zitrocin;
- Eryfluid;
- Ecositrin;
- Ka soocda;
- Arvitsin;
- AsitRus;
- Azimycin.