HIV iyo AIDS waa cudurro aan la daweynin, laakiin horumarkooda ayaa hoos u dhigi kara iyada oo loo marayo daaweyn gaar ah oo loo qaato daaweyn gaar ah. Daaweynta antiretroviral ee isku dhafan waxay ku lug leedahay isticmaalka saddex ama afar daroogo iyadoo ku xiran heerka cudurka iyo qiyaasta uu dhakhtarku soo qoray.
Sidee buu u shaqeeyaa daaweynta antiretrovoviral?
Fayruska difaacu wuxuu leeyahay mutagenicity sare. Tani waxay ka dhigan tahay in ay aad u adkeyso waxyeelooyin kala duwan oo waxyeellada leh waxayna awood u leedahay inay bedesho RNA-ga, sameynta isbeddel cusub oo macquul ah. Hanti ayaa si aad ah u adkeyneysa daaweynta HIV iyo AIDS, maadaama unugyada pathogenic ay si dhakhso ah ula qabsadaan daawooyinka la qaato.
Daaweynta Antiretroviral waa isu-geyn 3-4 dawo oo kala duwan, mid kasta oo ka mid ah mabda'a ah ee ficilka. Sidaa daraadeed, qaadashada daawooyin badan ayaa bixiya xakameyn la'aanta kaliya nooca ugu weyn ee fayruuska, laakiin sidoo kale mid ka mid ah isbeddellada ay sameeyeen intii lagu jiray horumarinta cudurka.
Goorma ayaa daaweynta daawada antiretroviral?
Dabcan, horaantii daaweynta infekshanka HIV-gu wuxuu bilaabmayaa, waxa fiican in uu joojiyo horumarka fayraska, wanaajiyo tayada iyo mudnaanta nolosha bukaanka. Marka la eego in calaamadaha ugu horeeya ee cudurku ku dhaco sida caadiga ah, daaweynta antiretroviral ayaa lagu qoraa qiyaastii 5-6 sano ka dib marka infekshanka, marar dhif ah waqtigaan waxaa la kordhiyaa 10 sano.
Dawooyinka daaweynta antiretroviral ee firfircoon
Daawooyinka waxaa loo qaybiyaa fasalo:
1. Ka hortagga transcriptase (nucleoside):
- Fiidkii;
- Tenofovir;
- Kivex;
- Retrovir;
- Abacabir;
- Zerit;
- Lamivudin;
- Trivizir;
- Emtriva.
2. Isku-duubnayaasha transcriptase aan-nukleoside dib u dhicin:
- Viramune;
- Stockrin;
- Delavirdine.
3. Xannibaadyada protease:
- Indinavir;
- Kaletra;
- Aptivus;
- Invisal;
- Ritonavir;
- Reyataz;
- Presista;
- Nelfinavir;
- Ageneraz;
- Telzir.
Ka hortagga fiyuusyada ayaa ka mid ah darajada ugu cusub ee daawooyinka loogu talagalay daaweynta firfircoon ee antiretroviral. Ilaa hadda hal daroogo oo loo yaqaan waa Fuzeon ama Enfuvirtide.
Saamaynta xun ee daaweynta antiretroviral
Dhibaatooyinka aan khatarta lahayn:
- finanka maqaarka;
- xanuunnada dheefshiidka;
- lipodystrophy;
- hyperlipidemia;
- caabbinta insulinta;
- lipoatrophy;
- boodhka nidaamka dareenka dhexe.
Saameyn xun:
- dhagxaan kellida ;
- silcinta dhuuxa lafta;
- necrosis ee beerka;
- acidaceous saca;
- Cudurka Fanconi;
- xanuunka loo yaqaan 'pancreatitis';
- ciriiriga;
- Stevens-Johnson syndrome.