Cudurada keena microbes iyo bakteeriya ayaa sabab u ah cudurada daran ee nidaamka neefsiga, nidaamka urojiinka iyo qaybaha kale ee jirka. Fluoroquinolones ee jiilka ugu dambeeya ayaa si waxtar leh uga hortagaya iyaga. Daawooyinkan daawada antimicrobiyanku waxay awoodaan in ay jabiyaan xitaa infekshannada u adkaysta quinolones iyo fluoroquinolones, waxay isticmaalaan dhowr sano ka hor.
Fluoroquinolones 4 jiilalka - nooca mukhaadaraadka?
Fluoroquinolones ayaa loo isticmaalay in lagu xakameeyo microbes tan iyo 1960-kii, inta lagu jiro xilligaas bakteeriyadu u muuqatay inay difaac u badan tahay daawooyinkan. Taasina waa sababta cilmi-baaristu ayan u joogin oo ay soo saaraan daroogooyinka cusub iyo kuwa cusub, iyagoo kordhinaya waxtarkooda. Halkan waxaa ku qoran magacyada jiilka ugu dambeeya ee fluoroquinolones iyo kuwa horay u soo maray:
- Diyaarinta jiilka koowaad (nalidixic acid, oxolinic acid).
- Daroogada 2-da ah (lomefloxacin, norfloxacin, ofloxacin, pefloxacin, iprofloxacin).
- Diyaargarowga jiilka seddexaad (levofloxacin, parfloxacin).
- Diyaargarowga jiilka afraad (moxifloxacin, hemifloxacin, gatifloxacin, sitafloxacin, trovafloxacin).
Tallaabada jiilka cusub ee fluoroquinolones waxay ku salaysan tahay isku-xidhnaanta DNA-ga bakteeriyada, taas oo miro-dhashaadku ay waayaan awoodda ay ku dhufanayaan isla markaana dhakhso u dhintaan. Iyadoo jiil walba, tirada bacilli oo ka soo horjeeda daawooyinka ay wax ku ool yihiin. Ilaa hadda, tani waa:
- E. coli;
- Pseudomonas aeruginosa ;
- gnofilnaya stick;
- shigella;
- salmonella;
- daacuunka daacuunka;
- Hominococci;
- meningococci;
- Campylobacter;
- Chlamydia;
- mycoplasma;
- pneumococci;
- staphylococci .
Maaha wax la yaab leh in fluoroquinolone badani ay ku jiraan liistada daawooyinka lagama maarmaanka ah ee muhiimka ah - iyadoon loo oggoleyn in lagu daaweeyo cudurka pneumonia, daacuunka, qaaxada iyo cudurrada kale ee halista ah. Noocyada kaliya ee daawada noocan oo kale ah ma saameyn karto dhammaan bakteeriyada anaerobic.
Maxay yihiin fluoroquinolone kiniinnada?
Ilaa hadda, kaniiniyada waxaa la siiyaa fluoroquinolones respiratory fluoro si loola dagaallamo infekshanka mareenka sare iyo hoose ee neefta, daawooyinka lagu daaweynayo infekshannada kudka-bukashada iyo
- Levofloxacin;
- Moxifloxacin;
- Sparfloxacin;
- Norfloxacin iyo kuwo kale.
Ka hor intaanad bilaabin daaweyn, si taxadar leh u baro khilaafaadka - daroogooyinka badan ee kooxdan laguma talinayo in la isticmaalo marka la jebinayo hawlaha maqaarka, kalyaha iyo cudurrada beerka. Carruurta iyo haweenka uurka leh, fluoroquinolones ayaa si adag u tilmaamaya sida uu dhakhtar u qoray markii ay timaado nolol badbaadinta.