Cudurka Addison ("bronze disease") waa cudur naadir ah oo ah nidaamka qanjirada, oo marka hore lagu sharraxay bartamihii qarnigii XIXda by dhakhtar-daweeyaha Ingiriisiga T. Addison. Dadka da'doodu u dhaxayso 20 ilaa 50 sano ayaa ah kuwa ugu nugul cudurka. Maxaa ku dhacaya jidhka leh cudurkan, maxay yihiin sababaha ay u dhaceen iyo qaababka casriga ah ee daaweynta, waxaan ka sii fekereynaa dheeraad ah.
Cudurka Addison - cudur-daarshowga iyo cudur-maskaxeedka
Cudurka Addison waxaa sababa dhaawacyo labada dhinac ah oo ku dhaca kortenska adrenal. Xaaladdan oo kale, waxaa jira hoos u dhac weyn ama dhamaystirka joojinta hormoonnada, gaar ahaan glucocorticoids (cortisone iyo hydrocortisone) nidaaminta borotiinka, carbohydrate iyo metabolism, iyo sidoo kale mineralocorticoids (deoxycorticosterone iyo aldosterone) oo ka masuul ah hannaanka dheef-shiidka biyaha.
Tan shanaad ee kiisaska cudurkaan waa asal aan la garaneynin. Sababaha la og yahay ee cudurada Addison, waxaan kala saari karnaa waxyaabaha soo socda:
- Dhaawaca ootimmoga ee lafdhabarta kortexyada;
- AIDS;
- waraabowga;
- adrenoleukodystrophy;
- qaaxada ee qanjidhada adrenal;
- amyloidosis ;
- sarkhoidosis;
- saarida qanjirrada adrenal;
- dhiigbaxyada qanjirrada adrenal;
- daaweynta muddada-dheer ee hormoonnada;
- dhaawacyo fangas ah.
Hoosudhaca wax soo saarka macdanta macdanta macdanta ayaa keeneysa xaqiiqda ah in jidhku uu lumiyo soodhiyam weyn, waa fuuqbax, iyo mugga dhiig wareega iyo geedi socodka kale ee pathological ayaa sidoo kale hoos u dhacaya. Maqnaanshaha synthesis of glucocorticoids waxay keenaysaa xad gudubka metabolism carbohydrate, dhibicda sonkorta dhiigga, iyo insufficiency insulin.
Calaamadaha Cudurka Adison
Sida caadiga ah, horumarinta cudurka Addison ayaa si tartiib tartiib ah u dhaca, dhowr bilood illaa dhowr sano, iyo calaamadaha ay badanaa la socdaan muddo dheer. Cudurku wuxuu dhici karaa marka jirku leeyahay baahi ba'an oo loogu talagalay glucocorticoids, taas oo la xidhiidha walwal ama walbahaar.
Calaamadaha cudurka waxaa ka mid ah:
- daal degdeg ah;
- daciifinta murqaha;
- xasuusta hoos u dhaca;
- miisaan lumis;
- carqaladaynta mareenka mindhicirka;
- cadaadiska dhiiga ee hooseeya;
- dareenka maqaarka (dhibco buluug ah) - waxay dhacdaa waqti dheer kahor muuqaalka calaamadaha kale;
- Soo jiidashada cuntada cusbada leh iyo cusbada;
- harraad;
- caadada aan caadi ahayn;
- tufaax gacmaha , madaxa;
- kaadi badan;
- gawaarida iyo kuwo kale.
Dhibaatada Addison
Haddii calaamadaha cudurku si degdeg ah u dhaco si dhakhso ah, maskaxda adrenocortical degdeg ah ayaa dhacda. Xaaladdan waxaa la yiraahdaa "dhibaatooyinka adduuniyaanka" oo ah nolol halis ah. Waxay muujinaysaa calaamadaha calaamadaha calaamadahaas sida xanuunka daran ee degdega ah ee dhabarka, caloosha ama lugaha, mataga iyo shubanka daran, luminta miyirka, lakabka cawliga ee carrabka, iwm.
Cudurka Addison - Ciladda cudurka
Haddii cudurrada Addison lagu tuhunsan yahay, tijaabooyinka shaybaarka ayaa la sameeyaa si loo ogaado hoos u dhaca heerarka sodium iyo heerarka potassium, hoos u dhaca gulukooska serum, wax yar oo ka mid ah corticosteroids ee dhiigga, kordhinta macdanta eosinophils, iyo kuwa kale.
Cudurka Addison - daaweynta
Daaweynta cudurku wuxuu ku salaysan yahay daaweynta hoormoonka daaweynta hoormoonka. Sida caadiga ah, la'aanta cortisol waxaa lagu bedelay hydrocortisone, iyo la'aanta corticosteroid macdanta
Iyadoo addison dhibicda, glucocorticoids xididdada iyo xajmiga badan ee xalalka saline leh ee la yiraahdo dextrose ayaa loo qoraa, kaas oo u oggolaanaya inuu hagaajiyo xaalada oo laga saaro halista nolosha.
Daaweyntu waxay ku lug leedahay cunto xaddidaysa isticmaalka hilibka iyo ka reebista baradhada duban, digirta, lowska, muuska (si loo yareeyo qaadashada potassium). Isticmaalka cusbada, karbohidraatka iyo fitamiinada, gaar ahaan C iyo B, ayaa sii kordhaya. Saadaalinta daaweyn ku filan oo waqtiyaysan ee cudurrada Addison waa mid aad u wanaagsan.